CAS:22204-53-1丨Naproxen

Naproxen is an organic compound that is soluble in a variety of organic solvents (e.g., ethanol, dimethylformamide, etc.) and is less soluble in water. The substance is chemically stable but may decompose or chemically react with other substances under certain environmental conditions.

Uses:

Photosensitiser applications: naproxen can be used as a photosensitiser and has a wide range of applications in the field of photosensitive materials and photosensitive electronics. It can produce specific chemical reactions or physical effects under specific light conditions, providing important material support for the development of technology in related fields.

Medical field:

Naproxen mainly has anti-inflammatory, analgesic and antipyretic effects. Its mechanism of action is through the inhibition of cyclooxygenases (COX-1 and COX-2), thereby reducing the synthesis of various types of inflammatory mediators such as prostaglandins and thromboxanes.

In pain relief, it is indicated for a wide range of mild to moderate pain conditions, including pain after dental extractions and other surgical procedures, primary dysmenorrhoea, headaches and low back pain.

In the treatment of arthritis, it is one of the most commonly used drugs for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, tendonitis, bursitis, and acute gouty arthritis, as it can effectively alleviate pain, swelling, and limitation of movement caused by these arthritic conditions.

In the treatment of inflammatory diseases, it can be used in the treatment of acute upper respiratory tract inflammation and other diseases with inflammatory reaction, to help reduce the symptoms of inflammation.

Method of Preparation:

It can be prepared by reacting 2 - oxonaphthalene with propionic anhydride under acidic conditions. During the reaction, the resulting ester acid ester compound is hydrolysed to give naproxen. The specific reaction conditions and process flow may need to be optimised and adjusted to ensure the quality and yield of the product.

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