CAS:75867-39-9丨4-((Trimethylsilyl)ethynyl)aniline

4-((Trimethylsilyl)ethynyl)aniline (CAS 75867-39-9) is an aromatic amine compound containing a silicon-ethynyl group, also known as 4-(2-Trimethylsilylethynyl)aniline. It has a molecular formula C₁₁H₁₅NSi and a molecular weight 189.33.
4-((Trimethylsilyl)ethynyl)aniline is commonly a light yellow crystalline solid at room temperature. Its melting point is 94–98°C, boiling point is 258.9°C at normal pressure, flash point is 110.4°C (>230°F), and density is 0.973 g/cm³. The molecular structure contains polar amino groups and non-polar trimethylsilyl ethynyl groups, making it highly soluble in organic solvents such as ethanol and ether and slightly soluble in water. It is sensitive to heat, light, and moisture.

Uses:

4-((Trimethylsilyl)ethynyl)aniline serves as a key reagent in organic synthesis and pharmaceutical intermediates. As a silicon-containing ethynyl building block, it is used to construct ethynyl-containing aromatic compounds. The trimethylsilyl group can act as a protective group or reaction site, enabling the generation of free ethynyl groups through desilylation reactions. In the pharmaceutical field, it is involved in the synthesis of nitrogen-containing heterocycles or aromatic derivatives.

Method of Preparation:

The preparation of 4-((Trimethylsilyl)ethynyl)aniline usually adopts organic synthesis chemical methods. The following is one of the common preparation methods:

React p-toluene and trimethylsilylacetylene first to synthesize 4-[(trimethylsilyl)ethynyl]toluene.

React 4-[(trimethylsilyl)ethynyl]toluene with ammonia to generate 4-[(trimethylsilyl)ethynyl]aniline.

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Can I get some samples?

Yes, we can provide free samples, you only need to pay the shipping cost.

What is your MOQ?

Our MOQ is 1 kilogram. However, we usually accept smaller quantities, such as 100 grams, on condition that 100% of the sample fee is paid.

What is the lead time?

Lead time: approx. 5 days after payment confirmation.

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