Isopropylmagnesium Bromide Solution For Chemical Raw Materials CAS 920-39-8

Products Description

What is Isopropylmagnesium bromide solution for Chemical Raw Materials CAS 920-39-8 ?

Isopropylmagnesium Bromide (CAS 920-39-8) is an organomagnesium compound also known as bromo(isopropyl)magnesium and magnesium, bromo(1-methylethyl)-. With a molecular formula of C₃H₇BrMg and a molecular weight of 147.3, it belongs to the alkyl Grignard reagent class. This compound typically exists as a dark gray to dark brown transparent solution in solvents like tetrahydrofuran (THF) or 2-methyltetrahydrofuran (2-MeTHF).
Isopropylmagnesium Bromide has a density of 0.982 g/mL (25°C, THF solution), a flash point of -17°C, and melting point of 114–116°C (pure form). It is soluble in aprotic solvents such as THF and diethyl ether but insoluble in hydrocarbons. Contact with water or alcohol triggers violent reactions, releasing flammable gases (e.g., propane) and forming magnesium hydroxide.

Basic Info

Isopropylmagnesium bromide solution for Chemical Raw Materials CAS 920-39-8

Uses

As a nucleophilic reagent, Isopropylmagnesium Bromide participates in three key reaction types:
Carbonyl Addition: Reacts with aldehydes, ketones, and esters to generate isopropyl alcohols (e.g., forming 2,3-dimethyl-2-butanol with acetone).
Metal-Catalyzed Coupling: Undergoes palladium/nickel-catalyzed cross-coupling with halogenated hydrocarbons to introduce isopropyl groups, supporting the synthesis of drug intermediates or complex hydrocarbons.
Asymmetric Ketone Formation: Reacts with acyl chlorides (e.g., benzoyl chloride) to produce asymmetric ketones like benzophenone derivatives.

Safety Information

Hazards:
It is flammable when wet (H260), highly corrosive (H314), and can cause skin burns and eye damage.
Vapor irritates the respiratory tract (H335), and is harmful if inhaled or ingested (H302/H332).
Operation specifications:
Use anhydrous solvents under inert gas protection, avoid static electricity and open flames.
Wear protective gloves, goggles and protective clothing, and thoroughly clean the contact parts after operation.
Storage conditions: Store in a cool and dry place after sealing, away from oxidants and acidic substances, and avoid long-term exposure to air.

Company Profile

Gneebio is an enterprise specialising in the research, development, production and sales of phytochemicals and fine chemicals.Our factory was established in 2016 and is located in Henan Province, covering an area of 3,600 square metres. We have a professional, well-equipped and high-quality R&D team with more than 10 years of R&D experience. Our reagent products are widely exported to many countries including the United States, Russia, Canada, Australia, Europe, etc., and we provide fast shipping services to our customers. We hope to establish long-term and mutually beneficial cooperation with more friends in the future and provide the best products and services for our customers.

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