Isopropenylmagnesium Bromide Solution For Chemical Raw Materials CAS 13291-18-4

Products Description

What is Isopropenylmagnesium bromide solution for Chemical Raw Materials CAS 13291-18-4 ?

Isopropenylmagnesium Bromide (CAS 13291-18-4) Also known as bromo(prop-1-en-2-yl)magnesium, this organomagnesium compound has a molecular formula of C₃H₅BrMg and a molecular weight of 145.28 g/mol. Belonging to the alkenyl Grignard reagent class, it is typically supplied as a 0.5 M or 1.0 M solution in tetrahydrofuran (THF) or 2-methyltetrahydrofuran (2-MeTHF).
Isopropenylmagnesium Bromide appears as a white-to-orange crystalline powder in its pure form, while solutions range from orange to dark gray. It has a density of 0.927–0.935 g/mL (25°C, THF solution), a boiling point of 67°C (azeotropic with THF), and a flash point of 2°C, making it highly flammable. The compound is soluble in aprotic solvents like THF and diethyl ether but reacts violently with water or alcohols, releasing flammable propene gas.

Basic Info

Isopropenylmagnesium bromide solution for Chemical Raw Materials CAS 13291-18-4

Uses

As a nucleophilic reagent, Isopropenylmagnesium Bromide participates in three key reaction types:
Carbonyl Addition: Reacts with aldehydes, ketones, and esters to form allyl alcohol derivatives (e.g., producing 2-methyl-3-butene-2-ol with acetone).
Metal-Catalyzed Cross-Coupling: Undergoes palladium- or nickel-catalyzed coupling with alkyl/aryl halides to introduce isopropenyl groups in synthesizing drug intermediates or complex olefins.
Regioselective Ring Opening: Used in asymmetric synthesis, such as the total synthesis of natural products like (+)-desepoxyasperdiol.

Safety Information

Hazards: Highly flammable (H225), reacts violently with water (H260), may cause skin burns (H314) and respiratory irritation (H335).
Handling precautions: Use under the protection of inert gas (such as nitrogen or argon), avoid contact with air and moisture, and keep away from fire.
Storage conditions: Usually stored in sealed bottled solution at 2–8°C, avoid high temperature and light.

Company Profile

Gneebio is an enterprise specialising in the research, development, production and sales of phytochemicals and fine chemicals.Our factory was established in 2016 and is located in Henan Province, covering an area of 3,600 square metres. We have a professional, well-equipped and high-quality R&D team with more than 10 years of R&D experience. Our reagent products are widely exported to many countries including the United States, Russia, Canada, Australia, Europe, etc., and we provide fast shipping services to our customers. We hope to establish long-term and mutually beneficial cooperation with more friends in the future and provide the best products and services for our customers.

Contact Us
Tel: +86-372-5055135

Mob: +86-13673325456

Email: sales@gneebio.com

FAQ