Pharmaceutical intermediates M-methylpropiophenone CAS:51772-30-6

3'-Methylpropiophenone (CAS No. 51772-30-6) Also known as m-methylpropiophenone and 1-(m-tolyl)propan-1-one, this organic ketone compound has a molecular formula of C10H12O and a molecular weight of 148.20 g/mol. It appears as a white to off-white crystalline powder with a faint bitter almond-like aroma and is soluble in most organic solvents such as alcohols, ethers, and ketones.
3'-Methylpropiophenone exhibits a boiling point of 230.3°C (760 mmHg) and a density of 0.963 g/cm³. Featuring the typical reactivity of ketone compounds, it participates in nucleophilic addition, condensation, and other reactions, making it useful for introducing keto structures in organic synthesis.

Uses:

As a pharmaceutical intermediate, 3'-Methylpropiophenone synthesizes drug molecules containing aromatic ketone structures. Additionally, it serves as an organic synthesis reagent for preparing fine chemicals or functional materials.

Method of Preparation:

A major method of preparation is by the reaction of acetophenone and methyl ethyl ketone. The specific preparation steps are as follows: Firstly, acetophenone and methyl ethyl ketone are reacted under alkaline or acidic conditions. Then, the product is obtained by appropriate extraction and distillation separation.

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