What is the difference between anisole (CAS 100-66-3) and toluene (108-88-3)?

Sep 09, 2025 Leave a message

Toluene (108-88-3) and anisole (CAS 100-66-3) are two common chemicals that are widely used in the chemical industry and have a presence in everyday life. Although they are similar in name, they actually have obvious differences in chemical structure and properties.

What is the difference between anisole (CAS 100-66-3) and toluene (108-88-3)?

Chemical structure
Toluene has the molecular formula C6H5CH3, while anisole has the molecular formula C6H5OCH3. It can be seen that toluene consists of a benzene ring and a methyl group, while anisole consists of a benzene ring and a methoxy group. This difference determines the difference in their behavior and properties in chemical reactions.

 

Physical Properties
Toluene is a colorless and transparent liquid with volatile and flammable properties and is commonly used as an organic solvent and raw material.
Anisole is a colorless solid, also has a certain volatility and solubility, commonly used in the synthesis of dyes and spices and other fields.

 

Uses
Toluene is mainly used in the preparation of styrene, p-xylene, o-xylene and other chemical raw materials, or as an organic solvent.
Anisole is often used as synthetic dyes, fragrances and pharmaceutical intermediates, etc. Because of their different properties and uses, there will be some differences in production and use.

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