Pharmaceutical grade 99% Pimobendan CAS NO.74150-27-9

The compound corresponding to CAS 74150-27-9 is Pimobendan, a cardiotonic drug used to treat heart failure with both vasodilatory and antiplatelet aggregation effects. Its molecular formula is C₁₉H₁₈N₄O₂ (molar mass 334.37 g/mol).
The free base form of Pimobendan appears as a white to off-white solid with a melting point of ~240–243°C (decomposes), while its hydrochloride salt melts above 300°C. This compound is slightly soluble in water but readily soluble in organic solvents such as dimethyl sulfoxide and methanol.

Uses:
Pimobendan acts as a selective inhibitor of phosphodiesterase 3 (PDE3), primarily used for treating chronic congestive heart failure-especially canine heart diseases (e.g., dilated cardiomyopathy, valvular heart disease).

Mechanism of action:

Usually, acetanilide and propionyl chloride are used as starting materials, and a benzimidazole and pyridazinone bicyclic system is constructed through multiple steps of reactions such as acylation, cyclization, nitration, reduction, and condensation, and finally the target product is condensed with p-methoxybenzaldehyde.

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