CAS:62778-11-4 | Pyridinium Poly(hydrogenfluoride)

Products Description

The substance corresponding to CAS No. 62778-11-4 is Hydrogen fluoride-pyridine, which is usually a colorless to light yellow transparent liquid, soluble in water and organic solvents such as ethanol and ether.
The molecular formula of Pyridinium Poly(hydrogenfluoride) is C5H6FN, and the molecular weight is 99.1062. Its physical and chemical properties include a density of 1.1, a boiling point of 115.3°C at 760 mmHg, and a flash point of 20°C. These properties make it have good stability and reactivity under specific conditions, and it is suitable for a variety of chemical reactions and industrial applications.

Basic Info

Uses

Organic synthesis reactions
Preparation of fluoroamines: Preparation of β-fluoroamines from amino alcohols, important in the field of pharmaceutical chemistry.
Acetylene fluorination: Participate in acetylene fluorination to synthesize fluorinated alkynes, as an organic synthesis intermediate, can be converted into complex organic fluorides.
Phenol fluorination: Used with hypervalent iodine (III) reagents for the para-substituted fluorination of phenol to prepare cyclohexadienone, which has potential value in drug synthesis.
As a fluorination reagent: It is widely used in the fluorination ring-opening reaction of oxygen-containing and nitrogen-containing three-membered rings (such as epoxyfluorination ring-opening), with mild conditions, high stereoselectivity and yield.
Silyl ether protecting group deprotection reaction: Cleavage of the silyl ether protecting group of alcohol, can selectively cleave the silyl ether.
N-Boc bond cleavage reaction: Cleavage of N-Boc bonds, and can also selectively cleave silyl ethers in its presence, which is used for the synthesis and modification of complex organic molecules.

Company Profile

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