CAS:20780-74-9 | 7-Bromoindoline-2,3-dione

The compound corresponding to CAS No. 20780-74-9 is 7-Bromoindoline-2,3-dione, with a molecular formula of C₈H₄BrNO₂ and a molecular weight of about 226.03 g/mol.
7-Bromoindoline-2,3-dione is yellow-red crystal with a melting point of 200°C. It is slightly soluble in water and easily soluble in organic solvents such as dimethylformamide (DMF).

Uses:

7-Bromoindoline-2,3-dione is mainly used as a pharmaceutical intermediate for the synthesis of drugs or organic materials containing indole structures. The bromine atoms and ketone groups in its molecules provide active sites for subsequent chemical reactions, and are suitable for electrophilic substitution or condensation reactions.

Method of Preparation:
There are many ways to prepare 7-bromo-2,3-dioxoindoline, the following is one of the commonly used methods:
7-Bromoindoline-2,3-dione is produced by the reaction of 2,3-dioxoindoline and bromoacetic acid.

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