CAS:29908-03-0丨S-Adenosyl-L-methionine

The corresponding compound of CAS 29908-03-0 is S-Adenosyl-L-methionine, with a chemical formula of C₁₅H₂₂N₆O₅S (adenosine part) and a complex salt of p-toluenesulfonic acid (C₇H₈O₃S) and sulfuric acid (H₂SO₄), with a total molecular formula of C₂₂H₃₄N₆O₁₆S₄ and a molecular weight of 766.80 g/mol.

S-Adenosyl-L-methionine is a white to off-white crystalline powder, which is easily soluble in water (solubility is about 50 mg/mL), slightly soluble in methanol, and insoluble in ethanol and acetone. The melting point is 247-249°C, stable under acidic conditions, and easily decomposed in alkaline environments.

Uses:

Liver disease treatment:
S-Adenosyl-L-methionine is used to improve intrahepatic cholestasis (such as primary biliary cirrhosis) and drug-induced liver injury, and relieves symptoms by promoting bile acid metabolism and antioxidant effects.
Mental illness:
As an adjuvant therapy, it improves depression and anxiety symptoms by regulating brain methylation levels, especially for patients resistant to antidepressants.
Arthritis:
Promotes cartilage repair, relieves joint pain and inflammation, and its mechanism includes inhibiting the release of inflammatory factors such as IL-6.

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