CAS:20816-79-9 | 1-Bromo-8-chloronaphthalene

1-Bromo-8-chloronaphthalene (CAS 20816-79-9) is a halogen-containing aromatic hydrocarbon derivative with molecular formula C₁₀H₆BrCl and molecular weight 241.51. Its molecular structure is based on a naphthalene ring (fused bicyclic benzene system), with bromine and chlorine atoms located at the 1- and 8-positions of the naphthalene ring, forming an ortho-dihalogenated structure.
1-Bromo-8-chloronaphthalene appears as a light yellow to white crystalline solid, melting point 87–88°C, boiling point 150–160°C (5–6 torr), and density ~1.592 g/cm³. It has low vapor pressure, remains stable at room temperature, is insoluble in water, and highly soluble in organic solvents such as ethanol, ether, and dichloromethane.

Uses:

Pharmaceutical intermediate: 1-Bromo-8-chloronaphthalene builds halogen-containing aromatic skeletons, commonly used in developing antibacterial, anti-inflammatory, or anti-tumor drugs. Halogen atoms enhance lipophilicity and biological activity of compounds.
Photoelectric material precursor: Adjusts molecular electronic properties via its halogenated naphthalene structure for synthesizing organic semiconductors or fluorescent materials.
Fine chemical raw materials: Prepares other halogenated naphthalene derivatives, such as peri-substituted naphthalene series compounds, for producing pesticides or specialty chemicals.

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