Dimethyl Sulfoxide (DMSO) Uses in Organic Chemistry
Dimethyl Sulfoxide (DMSO) is a commonly used polar aprotic solvent in organic chemistry as well as in many industrial chemical processes. Thanks to its excellent dissolving ability and good chemical stability, it is widely applied in pharmaceutical synthesis, chemical production, and laboratory research.
DMSO has the molecular formula (CH₃)₂SO and the CAS number 67-68-5. It appears as a colorless liquid with a relatively high boiling point and strong polarity, allowing it to dissolve a wide variety of compounds. Because of these characteristics, it is frequently used as a reaction solvent in organic synthesis.
What is Dimethyl Sulfoxide (DMSO)?
Dimethyl sulfoxide (dmso) is a common organic solvent, and the dmso molecule works as a ligand to bind to various metal ions through the oxygen or sulfur donor atom. It has exceptional dissolving power and can dissolve both polar and non-polar compounds.
Dimethyl sulfoxide properties:
- High polarity
- Excellent solubility
- High boiling point (189°C)
- Strong chemical stability
Because of these characteristics, DMSO is commonly used in organic synthesis and pharmaceutical research.
Why DMSO is Used as a Reaction Solvent?
DMSO is highly valued in organic chemistry for several important reasons.
Polar Aprotic Solvent
DMSO is classified as a polar aprotic solvent. This means it can stabilize ions while not donating hydrogen atoms, making it ideal for nucleophilic reactions.
High Reaction Efficiency
Many organic reactions proceed faster in DMSO due to its ability to enhance nucleophilic reactivity.
Wide Solubility Range
DMSO can dissolve:
- Organic compounds
- Inorganic salts
- Polymers
- Pharmaceutical intermediates
This property makes it extremely versatile in both laboratory and industrial processes.
Common Organic Reactions Using DMSO
DMSO is frequently used in several types of organic reactions.
SN2 Reactions
DMSO promotes nucleophilic substitution reactions by stabilizing ions and increasing nucleophile strength.
Oxidation Reactions
DMSO participates in well-known oxidation processes such as Swern oxidation.
Pharmaceutical Synthesis
In pharmaceutical manufacturing, DMSO is used as a solvent for reaction intermediates and drug synthesis.
DMSO Product Specifications
- Name: Dimethyl sulfoxide/DMSO
- CAS Number: 67-68-5
- Chemical Formula: C₂H₆OS
- Molecular Weight: 78.13 g/mol
- Appearance: Colorless liquid
- Density: 1.10 g/cm³
- Boiling Point: 189 °C
- Melting Point: 18.5 °C
- Refractive Index: 1.477 (20 °C)
- Solubility: Very soluble in water and many organic solvents
Packaging Options
- 200 kg drum
- 1000 kg IBC tank
- Bulk supply available
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Industrial Applications of DMSO
- Organic Synthesis: Dmso Organic Solvent is a crucial polar solvent widely used in organic synthesis. It dissolves numerous organic compounds and facilitates the progression of chemical reactions.
- Pharmaceutical Applications: In the medical field, dmso solvent serves as a solvent and carrier for pharmaceuticals, aiding drug penetration into biological tissues. Additionally, it is employed in topical treatments for conditions such as arthritis.
- Biochemical Research: DMSO is frequently employed as a solvent or additive in biochemical research, including cell culture, protein purification, and analysis.
- Health Supplements and Cosmetics: DMSO is occasionally incorporated into health supplements and cosmetics for its penetration properties and moisturizing effects.
- Industrial Applications: DMSO solvent also serves industrial purposes as a lubricant, solvent extractant, resin solvent, and additive.

DMSO bulk supply
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- Stable factory production capacity
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Related Chemical Products from Gneebio
Bulk Industrial buyers often purchase DMSO CAS:67-68-5 together with other solvents and intermediates.
Here are the most popular products:
| Product Name | CAS |
|---|---|
| Cyclohexanone (CYC) | 108-94-1 |
| Methyl Methacrylate (MMA) | 80-62-6 |
| 2-Methoxyethanol | 109-86-4 |
| Propionic Acid | 79-09-4 |
| Ethylene Glycol (Meg) | 107-21-1 |
| N, N-Dimethylacetamide (DMAC) | 127-19-5 |

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