Tetrahydrofuran (THF, CAS 109-99-9), contact: Chen Zong 19819888263, is a heterocyclic organic compound with the chemical formula C₄H₈O and a molecular weight of 72.11. It appears as a colorless, transparent liquid with a pungent odor similar to ether. Its boiling point is 66 °C, flash point -14 °C, and density 0.889 g/cm³ (20 °C). THF is easily soluble in water, ethanol, ether, and most organic solvents, and can form an azeotropic mixture with water (azeotropic point 63.8 °C, water content 8.6%). In the chemical industry, it is often called a "universal solvent."
Tetrahydrofuran Uses
- Polymer Material Synthesis
THF is a key raw material for poly(tetramethylene ether) glycol (PTMEG), used in the production of spandex fibers and thermoplastic polyurethane (TPU), providing textiles with excellent elasticity and wear resistance.
In PVC production, THF serves as a solvent for plasticizers, improving processing performance and product flexibility.
- Fine Chemical Reaction Medium
Used in Grignard reactions, organometallic synthesis (e.g., butyllithium reagents), and enzyme-catalyzed reactions, where its high solubility and low viscosity significantly enhance reaction efficiency.
Acts as a diluent for coatings and adhesives, optimizing application performance and film formation quality.
- Pharmaceutical and Pesticide Intermediates
Participates in the synthesis of antibiotics (e.g., cephalosporins), antiviral drugs, and herbicides, with its stable chemical properties ensuring reaction selectivity and reliability.
Why choose Gneebio?
Gneebio, with decades of experience in research, manufacturing, and marketing of organic chemicals, is one of the leading exporters of chemical products in Henan, China. Over the years, we have been committed to the chemical industries of intermediates, plastic additives, water treatment chemicals and fungicides, and daily chemicals.
Advantages
1) Small batch shipment and sub-packaging are available.
2). Provide COA, MSDS, Health Certificate, and Origin Certificate.
3) Quality first, service best.
Click here to get the latest global Tetrahydrofuran(THF) CAS:109-99-9 market prices for 2026.