What is MOPS Sodium Salt(CAS 71119-22-7)?

Jul 18, 2025 Leave a message

MOPS Sodium Salt (CAS 71119-22-7), short for 3-(N-Morpholino)propanesulfonic acid sodium salt, is a commonly used buffer in biological and biochemical research. It appears as a white, odorless crystalline powder with high solubility in water-easily dissolving to form clear solutions. It has good stability over a wide range of temperatures and pH levels, with a melting point around 270-275°C (decomposes). Its chemical structure includes a morpholine ring and a sulfonic acid group (as a sodium salt), which allows it to maintain a stable pH in the range of 6.5-7.9, making it ideal for biological systems.

 

1. Biological and Biochemical Research
MOPS Sodium Salt is widely used as a buffer in laboratory experiments involving cells, proteins, and enzymes. It helps maintain a constant pH in cell cultures, ensuring cells grow and function properly. For example, it's used in media for culturing mammalian cells, where a stable neutral pH is critical. It also supports enzyme reactions, as many enzymes are sensitive to pH changes-MOPS keeps the environment consistent, ensuring accurate results in tests like PCR or protein electrophoresis.

 

2. Electrophoresis Applications
In gel electrophoresis (a technique to separate DNA, RNA, or proteins), MOPS Sodium Salt is a key component of running buffers. It maintains the pH of the electrophoresis buffer, which is essential for the proper migration of molecules through the gel. Its compatibility with nucleic acids and proteins makes it a preferred buffer for agarose gel electrophoresis, commonly used in molecular biology labs to analyze DNA fragments.

 

High purity MOPS Sodium Salt CAS 71119-22-7

 

3. Pharmaceutical and Cosmetic Formulations
It finds use in pharmaceutical research and cosmetic products. In drug development, it's used to stabilize formulations of active ingredients that are sensitive to pH changes, ensuring the drugs remain effective during storage. In cosmetics, it helps balance the pH of products like lotions and serums, preventing irritation and maintaining the stability of ingredients such as vitamins or plant extracts.

 

4. Industrial and Analytical Uses
Beyond research, MOPS Sodium Salt is used in analytical chemistry as a reference standard for pH calibration. It's also employed in some industrial processes where a mild, non-toxic buffer is needed-for example, in the production of biological products like vaccines, where maintaining a stable pH is crucial for product safety and efficacy.

 

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MOPS Sodium Salt(CAS 71119-22-7)

 

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