Ethanolamine (CAS 141-43-5), also known as 2-Aminoethanol or Monoethanolamine (MEA), is an organic compound with both an amine group and a hydroxyl group. Its dual functional groups make it a versatile intermediate and formulation aid in the drug industry.
In pharmaceutical formulations, MEA is used primarily for buffering or preparation of emulsions. MEA can be used as pH regulator in cosmetics. It is an injectable sclerosant as a treatment option of symptomatic hemorrhoids.
Ethanol amine uses
PH Adjuster and Buffering Agent
In liquid pharmaceutical formulations, ethanolamine can be used to:
- Adjust pH to stabilize drug solutions and prevent degradation.
- Serve as a buffer in ophthalmic drops, injectables.
Solubilizing and Emulsifying Agent
Ethanolamine derivatives, such as ethanolamine soaps or fatty acid ethanolamides, act as emulsifiers and solubilizers in:
- Topical creams and ointments
- Medicinal shampoos and lotions
- Injectable formulations where lipid solubility is required
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