Is ACN (CAS 75-05-8) a stronger solvent than methanol?

Jan 13, 2026 Leave a message

Acetonitrile is a slightly stronger solvent than methanol. It is a little cleaner in the UV; you can go all the way down to 190 nanometers with acetonitrile (versus 210 nanometers for methanol). Acetonitrile has a little lower viscosity therefore requires less pressure.

 

 

Why is acetonitrile a good solvent?

 

Acetonitrile is a colorless, transparent organic solvent with the chemical formula CH₃CN. High-purity acetonitrile typically contains over 99.9% acetonitrile. As a polar solvent, ACN exhibits excellent solubility and can dissolve numerous organic and inorganic compounds, such as fatty acids, aromatic and aliphatic compounds, and weakly corrosive inorganic substances.

 

ACN (CAS 75-05-8)
ACN (CAS 75-05-8)

 

What are the chemical properties of acetonitrile?


Acetonitrile (ACN) is a polar solvent with remarkable chemical inertness; however, under certain conditions, it readily undergoes electrophilic addition or nucleophilic substitution reactions. Additionally, it serves as an excellent hydrogen ion acceptor. High-purity acetonitrile has a boiling point of 81.6°C, a relative density of 0.786, and exists as a liquid at room temperature. With a dielectric constant of 37.5, it is a polar solvent that is insoluble in many nonpolar organic solvents but readily soluble in water.

 

 

What is ACN used for?

 

  • In scientific research, ACN serves as an organic solvent, reaction medium, and extractant. As a reaction medium, it facilitates organic chemical processes such as substitution, oxidation, and addition reactions. High-purity acetonitrile is also employed in high-performance liquid chromatography (HPLC) for separating and quantifying compound components.
  • In industrial production, high-purity acetonitrile serves equally vital purposes. It functions as a key raw material for manufacturing certain organic compounds and synthetic fibers (e.g., nylon). Furthermore, it finds extensive applications in electrochemistry, electroplating, foundry processes, synthetic rubber production, plastics manufacturing, and pharmaceuticals.

 

In summary, high-purity acetonitrile is an organic solvent with broad applicability. Its chemical properties determine its significant role across scientific research and industrial production sectors.

 

Is ACN acetonitrile (CAS 75-05-8) ?

 

Why choose Gneebio?

Gneebio, with decades of experience in research, manufacturing, and marketing of organic chemicals, is one of the leading exporters of chemical products in Henan, China. Over the years, we have been committed to the chemical industries of intermediates, plastic additives, water treatment chemicals and fungicides, and daily chemicals.

 

Acetonitrile (CAS 75-05-8) Manufacturing
Acetonitrile (CAS 75-05-8) Manufacturing

 

Advantages

1) Small batch shipment and sub-packaging are available.
2). Provide COA, MSDS, Health Certificate, and Origin Certificate.
3) Quality first, service best.

 

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