Can DMSO (dimethyl sulfoxide) be dissolved in water?

Nov 26, 2025 Leave a message

 

What is DMSO (dimethyl sulfoxide) ?

Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high boiling point. DMSO solvent has the unusual property that many individuals perceive a garlic-like taste in the mouth after contact with the skin.

 

What Is DMSO (Dimethyl Sulfoxide) ?

 

Can DMSO (dimethyl sulfoxide) be dissolved in water?

Dimethyl sulfoxide (DMSO) is soluble in water and miscible with water in any proportion. It is a highly polar, non-protonic solvent.

Solubility Characteristics
The molecular structure of DMSO endows it with strong polarity and hydrophilicity, resulting in the following water solubility properties:

  • Complete Miscibility: At room temperature, it is completely miscible with water in any proportion, forming a homogeneous, transparent solution.
  • Chemical Stability: It does not undergo chemical reactions when mixed with water at room temperature, but may decompose under high temperatures or acidic conditions.
  • Hygroscopicity: At 20°C, it absorbs moisture from the air equivalent to 70% of its own weight, further demonstrating its high affinity for water.

 

Dimethyl Sulfoxide Applications: As a "universal solvent," its water-soluble properties find extensive use in pharmaceuticals, chemical engineering, and other fields-such as serving as a drug carrier or reaction medium.

 

 

DMSO (dimethyl sulfoxide) properties

Property Description
Chemical Name Dimethyl Sulfoxide
Abbreviation DMSO
CAS Number 67-68-5
Molecular Formula C₂H₆OS
Molecular Weight 78.13 g/mol
Appearance Colorless, transparent liquid
Odor Slight sulfur-like odor
Melting Point 18.5°C
Boiling Point 189°C
Flash Point 95°C (closed cup)
Density 1.095 g/cm³ at 20°C
Solubility Miscible with water, ethanol, acetone, chloroform
Refractive Index 1.479 (20°C)
Purity (Industrial Grade) 99.0% min
Purity (Pharma/High Purity) 99.9% min
Stability Stable under normal conditions
Hazard Classification Low toxicity; irritant to skin & eyes

 

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DMSO CAS:67-68-5

 

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