CAS 2546-56-7 | 4-Chloro-3-fluoropyridine

Products Description

4-Chloro-3-fluoropyridine, with a CAS number of 2546-56-7, has a molecular formula of C₅H₃ClFN and a molecular weight of 131.534. It belongs to pharmaceutical intermediates, other intermediates, and synthetic material intermediates.
In terms of physical and chemical properties, 4-chloro-3-fluoropyridine liquid is transparent to light-yellow liquid. Its density is 1.333g/mL, measured at 25°C; the melting point is -24°C; the boiling point is 138.9°C under the pressure of 760mmHg; the refractive index is 1.503; the flash point is 37.8°C; and the acidity coefficient (pKa) is predicted to be 1.93±0.10.

Basic Info

Safety Information

• 4-Chloro-3-fluoropyridine is irritating to the skin and eyes. Appropriate personal protective equipment, such as gloves and goggles, should be worn during operation.
• In case of contact with skin or eyes, rinse immediately with plenty of water.
• Keep away from fire and oxidants during storage in a dry, cool place.

Uses

• Drug synthesis intermediate: Fluorine and chlorine atoms in the structure of Pharmaceutical intermediates 4-Chloro-3-fluoropyridine endow it with special chemical activity and it can be involved in various drug-synthesis reactions. For example, it can react with compounds containing amino, hydroxyl, and other functional groups through a series of chemical reactions to construct complex drug molecular structures.
• Synthetic antibacterial drugs: They can be used to synthesize drugs with antibacterial activity. The fluorine and chlorine atoms it contains can enhance the ability of drugs to bind to bacterial targets, thereby improving the antibacterial effect. In the synthesis of some new quinolone antibacterial drugs, 4-Chloro-3-fluoropyridine is used as a starting material or key intermediate to help construct molecular structures with specific pharmacological activities to combat drug-resistant bacteria.
• Synthetic antiparasitic drugs: They also play a role in the research development and synthesis of antiparasitic drugs. It can react with other compounds containing nitrogen, sulfur, and other heteroatoms to generate active molecules that can interfere with the physiological metabolic process of parasites, and is used to treat parasitic diseases such as malaria and schistosomiasis.

Company Profile

Gneebio is an enterprise specialising in the research, development, production and sales of phytochemicals and fine chemicals.Our factory was established in 2016 and is located in Henan Province, covering an area of 3,600 square metres. We have a professional, well-equipped and high-quality R&D team with more than 10 years of R&D experience. Our products are widely exported to many countries, such as the United States, Russia, Canada, Australia, Europe, etc., and we provide customers with fast shipping services. We hope to establish long-term and mutually beneficial cooperation with more friends in the future, and provide the best products and services for our customers.

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