CAS:182281-01-2 | 4-(2-Tetrahydropyranyloxy)phenylboronic Acid

Properties

-Appearance: 4-(2-Tetrahydropyranyloxy)phenylboronic Acid is a white crystalline solid
-Solubility: Soluble in ethanol, ketones and organic solvents, insoluble in water
-More Information:Its CAS number is 182281-01-2, its EINECS number is 145-852-6, its chemical formula is C₁₁H₁₅BO₄, and its molecular weight is 222.05. Its density is predicted to be 1.21±0.1 g/cm3, its melting point is in the range of 117-124°C, its boiling point is expected to be 411.3±55.0°C, and its flash point is 202.5°C.

uses：

Organic synthesis intermediate

• Participate in coupling reactions: As an aromatic boronic acid compound, 4-(2-Tetrahydropyranyloxy)phenylboronic Acid can participate in various carbon-carbon bond formation reactions such as Suzuki-Miyaura coupling reaction, and is widely used in the fields of natural product total synthesis, drug synthesis, and functional material synthesis.
• Functional group transformation: The tetrahydro-2H-pyran-2-oxy group in its molecule can be transformed or removed under certain conditions, providing a variety of possibilities for the synthesis of organic compounds with different functional groups.

Application in the pharmaceutical field

• Drug research and development: In pharmaceutical chemistry, it is an important raw material for the synthesis of molecules with potential biological activity. It can be used to construct drug intermediates with specific structures and functions, such as in the research and development of some anti-tumor drugs, anti-inflammatory drugs, and nervous system drugs.
• As a drug carrier: Its structural characteristics make it possible to be used as a part of a drug carrier. By combining with other targeted or functional groups, it can achieve functions such as targeted delivery and sustained release of drugs, thereby improving the efficacy of drugs and reducing toxic side effects.

Safety Information:

- 4-(2-Tetrahydropyranyloxy)phenylboronic Acid is an organic compound, which is generally toxic and irritating.
- When operating, personal protective equipment such as protective gloves, glasses and protective masks should be worn to avoid direct contact with the skin and inhalation of vapor.
- When storing and transporting, avoid contact with oxidants, strong acids and other substances to prevent dangerous reactions.
- During use, pay attention to good ventilation conditions to reduce the accumulation of organic solvent vapor. If an accident occurs, take appropriate emergency measures in time, such as washing eyes, flushing skin, etc., and seek medical assistance.

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