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3-(1-Piperazinyl)-1,2-benzisothiazole CAS 87691-87-0

3-(1-Piperazinyl)-1,2-benzisothiazole CAS 87691-87-0

3-(1-Piperazinyl)-1,2-benzisothiazole is employed in the synthesis of ziprasidone (Z485000, HCl salt, monohydrate), serotonin (5HT2) and dopamine (D2) receptor antagonists.

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Product Introduction
Products Description

 

3-(1-Piperazinyl)-1,2-benzisothiazole is an organic compound with the following properties:

APPEARANCE: It is a solid, commonly white or yellow crystalline substance.
SOLUBILITY: 3-(1-piperazinyl)-1,2-benzisothiazole has low solubility in water, but can be dissolved in organic solvents such as ether, chloroform and dimethylhydrazine.
STABILITY: It is relatively stable at room temperature and is insensitive to light, heat and air.

87691-87-0
3-(1-Piperazinyl)-1,2-benzisothiazole
Basic Info

 

ITEMS

SPECIFICATION

CAS 87691-87-0
Chemical Formula C11H13N3S

Melting point

89.0 ~ 93.0 °C

Storage temp.

2-8°C

Density

1.256

Boiling point

320.2 °C

pka

8.52

 

Uses 

 

A common method of preparing 3-(1-piperazinyl)-1,2-benzisothiazole is to react 1-piperazinyl-3-bromobenzene with alkyl isothiocyanate dehydrated sodium chloride.

3-(1-Piperazinyl)-1,2-benzisothiazole is an antimicrobial agent. It stops bacteria from growing by blocking enzymes like DNA gyrase and topoisomerase IV. It is effective against bacteria like Escherichia coli, Enterococcus faecalis, Streptococcus pneumoniae, Bacillus subtilis, Staphylococcus epidermidis, and Pseudomonas aeruginosa. It also stops the growth of Mycobacterium tuberculosis in culture.

 

3-(1-Piperazinyl)-1,2-benzisothiazole = 98

 

Safety Information


During handling, appropriate personal protection measures should be taken, such as wearing gloves, protective glasses and protective clothing. 3-(1-Piperazinyl)-1,2-benzisothiazole should be stored and handled properly to avoid contact with oxidants, strong acids and strong bases.

 

Company Profile

 

Gneebio is a professional chemical raw material manufacturer and global distributor. Our company is located in Henan Province, China. We have multiple partner chemical factories in Henan, covering an area of 3,600 square meters, providing customers with a one-stop chemical procurement service, including mixing, repackaging, storage, and distribution.
Our hot-selling products include aromatic hydrocarbons (Naphtha (petroleum), Benzene, Toluene, o-Xylene, Styrene, Cyclohexane, Cyclohexanone, Epsilon-Caprolactam, 2-Anilinoethanol, etc.), alcohols (Ethylene Glycol, 1-Butanol, 2-Methyl-1-Propanol, Ethyl Alcohol, etc.), phenols and ketones (Phenol, Propafenone, Bisphenol A, Phenyl Methacrylate, Methyl Isobutyl Ketone, Phenolic Resin, etc.), and petrochemicals. We hope to establish long-term and mutually beneficial cooperation with more friends in the future and provide the best products and services for our customers.
Please contact us if you need any.

 

New Disulfide Route to 3-(1-Piperazinyl)-1,2-benzisothiazole

 

3-(1-Piperazinyl)-1,2-benzisothiazole = 98

 

FAQ

 

What are the quality requirements?

We can provide 1 gram, 10 grams and 100 grams according to your requirements.

 

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We accept Western Union, bank transfer, credit card, PayPal and trade deposit orders on Alibaba.

 

What is the lead time for delivery?

For most chemicals we have in stock, it takes about 1-3 days after payment confirmation.

 

Can we visit your company/factory before placing an order?

A: It is our honor. We sincerely welcome you to visit Gnee Chemical Company and we guarantee you will have a pleasant trip to China!

 

Is it possible to put our brand on your products?

Yes. If you can meet our minimum order quantity, we can print your logo on the products and packaging.

 

How to confirm the product quality before placing orders?

You can get free samples for some products, you only need to pay theshipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacturethe products according to your requests.

 

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