Products Description
The compound corresponding to CAS 139911-29-8 is 4-Fluoro-2-methylphenylboronic Acid, with a molecular formula of C₇H₈BFO₂ and a molecular weight of 153.95 g/mol. It is an organic boron compound with a fluorine atom and a methyl substituent on the benzene ring, as well as a boron hydroxyl structure.
4-Fluoro-2-methylphenylboronic Acid is a white to off-white crystalline powder at room temperature and has weak acidity (pKa is about 8.5). Its melting point is 148–152°C, slightly soluble in water, easily soluble in polar organic solvents such as ethanol, methanol, and tetrahydrofuran (THF), soluble in dichloromethane, but insoluble in non-polar solvents such as n-hexane.
| Molecular Formula | C7H8BFO2 |
| Molar Mass | 153.95 |
| Density | 1.20±0.1 g/cm3(Predicted) |
| Melting Point | 191-196°C(lit.) |
| Boling Point | 277.4±50.0 °C(Predicted) |
| Flash Point | 121.6°C |
| Solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.00218mmHg at 25°C |
Uses:
Pharmaceutical intermediates
Antifungal drugs: 4-Fluoro-2-methylphenylboronic is a key intermediate of Tavaborole and participates in the construction of its side chain. Tavoroborole is a topical antifungal drug used to treat onychomycosis. Its mechanism of action involves inhibiting fungal protein synthesis.
Other drugs: When synthesizing antidepressants and antiviral drugs, its fluorinated benzene ring structure can enhance the lipid solubility and bioavailability of drug molecules.
Materials Science
Polymer modification: As a cross-linking agent or antioxidant, it improves the thermal stability and mechanical properties of polymer materials.
Catalyst carrier: Its boron hydroxyl group can coordinate with metal ions and is used to load catalysts such as palladium and rhodium to improve catalytic efficiency.
About Us
Gnee Chemical is located in Henan Province, China. We are a professional import and export trading company, mainly selling plant extracts, food additives, chemical intermediates and other products. We have passed theIS0-9001 quality system certification, with products sold to sev-eral dozens of countries and regions in North and South Ameri-ca, Europe, Asia, Australia and South Africa, hence enjoyingextremely high reputation and popularity on the internationalstage.
We are looking forward to cooperating with you and establishing a win-win relationship with you. Please rest assured that we will take your order seriously.
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Can I request samples?
Yes, absolutely! We offer free samples of specified quantities. You only need to cover the freight charges.
Which documents are provided?
We provide essential documents such as Certificate of Analysis (COA), Technical Data Sheet (TDS), Material Safety Data Sheet (MSDS), and more upon request.
What is your Minimum Order Quantity (MOQ)?
Typically, our MOQ is one standard package. However, we understand the importance of testing before committing to a mass order, so we offer free samples for your evaluation.
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