Products Description
4 - Chloropicolinamide (CAS 99586 - 65 - 9) is also known as 4 - Chloropyridine - 2 - carboxamide, with a molecular formula of C₆H₅ClN₂O and a molecular weight of 156.57.
4 - Chloropicolinamide is a solid, white in color, with a melting point of 158°C to 162°C. Its density is about 1.4 ± 0.1 g/cm³, its boiling point is 298.1 ± 25.0 °C (760 mmHg), its flash point is 134.1 ± 23.2 °C, and its vapor pressure is 0.0 ± 0.6 mmHg (25°C).


Basic Info
|
ITEMS |
SPECIFICATION |
| CAS | 99586-65-9 |
| Chemical formula | C6H5ClN2O |
| Molecular weight | 156.57 |
| Density | 1.381 g/cm3 |
| bp | 298.1ºC at 760 mmHg |
| mp | 148-152ºC |
| fp | 134.1ºC |
| Refractive Index | 1.588 |
| Storage condition | Inert atmosphere,Room Temperature |

Uses and Preparation
Uses:
4 - Chloropicolinamide is of great significance in the field of organic synthesis, especially in pharmaceutical synthesis. It is a key intermediate in the synthesis of regorafenib and sorafenib, drugs for the treatment of hepatocellular carcinoma.
Method of Preparation:4-Chloropicolinamide can combine with other compounds through specific reactions to gradually build a drug molecule structure with therapeutic activity. During synthesis, it can be obtained by reacting 4-chloro-2-pyridinecarboxylic acid with ammonia water with a yield of about 96%; it can also be obtained by reacting 4-chloropyridine-2-carboxylic acid methyl ester and ammonia under certain conditions with a yield of about 85%.
Company Profile
Established in 2014, Gnee Chem is located in Anyang City, Henan Province. Our products are exported to dozens of countries and regions such as North and South America, Europe, Asia, Australia and South Africa. We are a professional import and export trading company, mainly selling plant extracts, food additives, chemical intermediates and other products.


FAQ
Can I have a sample for testing?
A: Yes! Testing allows you to visualize the effectiveness of the application. In fact, the samples are free of charge and you only need to pay for the courier fee.
Can you provide product testing method?
A:Yes: Of course, we will provide lab test methods for our customers.
If I want to use my own specified labeling or packaging, can I?
A: Yes, you can. Yes, we will use the specified labeling and packaging according to your requirements.
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