CAS:5000-66-8 | 2-Bromo-1-(2-chlorophenyl)ethanone

Products Description

The substance corresponding to CAS No. 5000 - 66 - 8 is 2 - Bromo - 1-(2 - chlorophenyl)ethanone. It also has aliases such as 2 - Chloro - 2 - bromoacetophenone. Its molecular formula is C8H6BrClO, its molecular weight is 233.49, and its MDL No. is MFCD00832993.
Regarding its physical and chemical properties, 2 - Bromo - 1-(2 - chlorophenyl)ethanone is a colorless liquid. Its melting point is 162 - 166 ºC (20 mmHg). Its boiling point is 105 °C at 1 mmHg and 248.9±15.0 °C at 760 mmHg. Its density at 25 °C is 1.602 g/mL. Its refractive index at 20 °C with respect to the sodium D - line is 1.5900. The flash point is greater than 230 °F, specifically 104.3±20.4 °C. The vapor pressure is 0.0±0.5 mmHg at 25°C, the LogP value is 2.62, and the PSA value is 17.07.

Basic Info

Safety Information

Hazard code: C.
Risk statement: R34, causes burns.
Safety statement: S26, S36/37/39, S45, etc., in case of contact with eyes, rinse immediately with plenty of water and seek medical attention; wear suitable protective clothing, gloves and eye/face protection; in case of accident or feeling unwell, seek medical attention immediately, etc.
WGK Germany: 3.
Hazard category: 8.
Packing group: II.

Uses

Antihistamines: In the synthesis of some antihistamines, 2-Bromo-2'-chloroacetophenone serves as a key intermediate. It facilitates the introduction of specific functional groups and structural fragments through a series of chemical reactions to produce drug molecules with antihistamine activity. These molecules can help relieve allergic symptoms such as sneezing, runny nose, and itchy skin.

Local anesthetics: 2-Bromo-2'-chloroacetophenone is involved in the synthesis of certain local anesthetics. Through reactions with other compounds, it helps form molecular structures with anesthetic effects, which can temporarily block nerve conduction and induce localized pain relief. These anesthetics are commonly used in surgery, dental treatments, and other medical applications.

Company Profile

Gneechem, located in Henan Province, China, is part of the GNEE Group, with 22 years of experience in foreign trade, specializing in providing high-quality chemical raw materials and professional trading services to customers around the world. We supply basic chemical raw materials, fine chemicals and specialty chemicals for a wide range of industries.We are ISO9001 certified and have been recognized by a number of authoritative qualifications at home and abroad, making us a trusted partner of our customers.

FAQ