CAS:1195768-18-3 | Methyl 3-amino-2-fluorobenzoate

Products Description

The substance corresponding to CAS No. 1195768 - 18 - 3 is Methyl 3 - amino - 2 - fluorobenzoate. Its chemical formula is C₈H₈FNO₂, molecular weight is 169.15, EINECS No. is 629 - 868 - 4, and MDL No. is MFCD12923265.

In terms of physical properties, Methyl 3 - amino - 2 - fluorobenzoate has a colorless to light orange to yellow appearance and is a transparent liquid or white solid at room temperature. The density is 1.264±0.06 g/cm³ (Predicted), the boiling point is 282.6±25.0 °C (Predicted), the refractive index is 1.5570 - 1.5610, and the pKa is 2.06±0.10 (Predicted).

In terms of chemical properties,3-Amino-2-fluorobenzoic acid methyl ester has the typical chemical properties of esters, amino groups and fluorine atoms. Amino groups can undergo acylation, alkylation and other reactions, fluorine atoms can undergo substitution reactions under certain conditions, and ester groups can undergo hydrolysis, alcoholysis and other reactions.

Basic Info

Safety Information

- 2-Fluorobenzidine has low toxicity but still needs to be handled and stored with care.
- Avoid direct contact with skin and eyes during operation and preparation.
- Wear appropriate protective gloves, goggles, and lab coats when using.
- Please follow laboratory operating procedures and safe operating procedures.
- Storage conditions are to keep in a dark, inert atmosphere, in a freezer below -20°C

Uses

Methyl 3 - amino - 2 - fluorobenzoate is an important compound for the synthesis of dabrafenib, which is a kinase inhibitor and is commonly used to treat certain forms of melanoma, non - small cell lung cancer and thyroid cancer.

Company Profile

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