CAS: 887572-60-3 5-METHOXY-1H-BENZOIMIDAZOLE-2-CARBOXYLICACID

The corresponding compound of CAS 887572-60-3 is 5-Methoxy-1H-benzo[d]imidazole-2-carboxylic acid, with a molecular formula of C9H8N2O3 and a molecular weight of 192.17. The structure contains a methoxy group at the 5th position of the benzimidazole mother ring and a carboxylic acid group at the 2nd position.
5-Methoxy-1H-benzo[d]imidazole-2-carboxylic acid has the appearance of a white to light yellow solid, which is soluble in polar organic solvents such as dimethyl sulfoxide and methanol, and slightly soluble in water. As a nitrogen-containing heterocyclic carboxylic acid compound, its carboxylic acid group can undergo esterification and amidation reactions, and the methoxy group can act as a directing group to participate in electrophilic substitution reactions.

Uses:

5-Methoxy-1H-benzo[d]imidazole-2-carboxylic acid is used to construct biologically active molecules containing a pyridine skeleton. For example, its acetyl group can participate in condensation, reduction and other reactions to prepare antifungal drugs or insecticides.

Method of Preparation:
5-METHOXY-1H-BENZOIMIDAZOLE-2-CARBOXYLICACID can be prepared by condensation reaction of aniline and formaldehyde to produce a benzimidazole ring, and then the target product can be obtained by formylation reaction of it. The specific synthesis steps can be adjusted according to the needs and conditions.

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