Products Description
CAS:1597403-47-8 ISRIB (trans-isoMer)
The substance corresponding to CAS 1597403-47-8 is ISR Inhibitor, which is widely used in the field of scientific research and is used as a PERK inhibitor to analyze the cell stress signaling pathway. ISRIB (trans-isomer) has relatively good characteristics in pharmacokinetic experiments and has good bioavailability in vivo.
|
ITEMS |
SPECIFICATION |
|
Boiling point |
719.0 °C |
|
pka |
13.63 |
|
storage temp. |
2-8°C |
|
density |
1.33 g/cm3 |
Uses of CAS:1597403-47-8
Research field:
As a PERK inhibitor, it is used to explore the signaling pathway mechanisms related to cell stress, such as unfolded protein response and integrated stress response.
Study neurodegenerative diseases, explore abnormal changes in cell stress mechanisms during the occurrence of diseases, and potential therapeutic targets and intervention strategies.
Explore cognitive function and memory enhancement mechanisms to provide a theoretical basis for the treatment of neurocognitive disorders.
Drug research and development field: It can be used as a potential drug for the treatment of depression and improve the behavioral manifestations of learned despair associated with depression.
Inspection methods
High-performance liquid chromatography (HPLC): After dissolving the sample, inject it into the instrument, compare the retention time and peak area of the standard, use a reverse phase column, acetonitrile, water, etc. as the mobile phase, and detect at wavelengths such as 254nm or 220nm to determine the content and purity.
Gas chromatography (GC): Suitable for volatile samples, after vaporization, separated by a chromatographic column, identified and quantified according to the retention time and response signal, and often requires derivatization such as silanization.
Melting point determination method:By determining the melting point of ISRIB and comparing it with the known standard melting point, the purity of the sample can be preliminarily determined. Generally speaking, ISRIB with higher purity has a narrower melting point range and a clear melting point value. If the sample contains impurities, its melting point will be lower and the melting point range will be wider.
Company Profile
GNEE has more than 10 years of experience in the field of Organic Chemistry.
Arranging orders and shipments in time according to customers' requirements, providing complete customs clearance documents according to export policies of different countries.
With 1000 square meters of office and 3000 square meters of warehouse to ensure your efficiency and warehousing.
Wide range of products: more than 500 kinds of products with competitive price, and we can take full responsibility if there is any quality problem with our ISRIB (trans-isoMer).
Provide price trends to ensure that our customers keep abreast of market information.
FAQ
1.Can you provide product testing method?
-A:Yes: Of course, we will provide lab test methods for our customers.
2. How do I get a price?
-We usually quote within 24 hours of receiving your inquiry (excluding weekends and holidays).
-If you need a price urgently, please email or contact us by other means so that we can quote for you.
3. What is your delivery time?
-It depends on the number of orders and the season in which you place your order.
-Usually, orders can be dispatched within 7-15 days for small orders and 25 days for large orders.
4. What is the shipping method?
-You can ship by sea, air, or express (EMS, UPS, DHL, TNT, FEDEX, etc.).
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