Pharmaceutical intermediates Scopine Hydrochloride CAS 85700-55-6

The compound corresponding to CAS 85700-55-6 is Scopine Hydrochloride, a chiral organic compound containing a nitrogen heterocyclic ring. Its molecular formula is C₈H₁₄ClNO₂, molecular weight is 191.66 g/mol, and its chemical structure contains a tricyclic skeleton and a quaternary ammonium ion, which is formed by scopolamine and hydrochloric acid.
Scopine Hydrochloride is a white to off-white crystalline powder with a melting point of 207–213°C (decomposition). It is easily soluble in water and slightly soluble in organic solvents such as methanol and ethanol. Its aqueous solution is acidic.

Uses:

Pharmaceutical intermediates: Scopine Hydrochloride is a key intermediate of tiotropium bromide (antiasthmatic drug) and is used to synthesize peripheral anticholinergic drugs.
Pharmacological action: After salt formation, it is difficult to pass through the blood-brain barrier and mainly acts on the peripheral nervous system to relieve gastrointestinal, bile duct and urinary tract spasms.

Method of Preparation:
The preparation of Scopine Hydrochloride can be obtained by the reaction of scopolamine with hydrochloric acid, which can be carried out using a dilute hydrochloric acid solution and at the appropriate temperature and time.

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