CAS:153505-37-4丨4-Bromo-5-fluorobenzene-1,2-diamine

4-Bromo-5-fluorobenzene-1,2-diamine is also known as 4-bromo-5-fluoro-1,2-phenylenediamine. Its CAS number is 153505-37-4, its molecular formula is C₆H₆BrFN₂, and its molecular weight is 205.0276.
4-Bromo-5-fluorobenzene-1,2-diamine is white to pale yellow crystal or powdery solid, with a melting point of 108-110°C and a boiling point of 297°C. It has good solubility in organic solvents (such as alcohols and chlorinated hydrocarbons), but its solubility in water is very low, belonging to the slightly soluble level.

Uses:

4-Bromo-5-fluorobenzene-1,2-diamine can be used as an organic synthesis intermediate in the pharmaceutical field. It can be used to synthesize compounds with potential biological activity and provide a basis for drug research and development.

Method of Preparation:

The preparation method of 4-Bromo-5-fluorobenzene-1,2-diamine mainly involves bromo- and fluoro-para substitution reactions. The specific steps include reacting o-phenylenediamine with bromomethane and sodium fluoride, and the final product is obtained after a series of multi-step reactions.

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