CAS:13361-64-3丨PROPARGYLTRIMETHYLSILANE

CAS: 13361-64-3 corresponds to alkyne Propargyltrimethylsilane, whose molecular formula is C₆H₁₂Si and molecular weight is 112.245 g/mol.

PROPARGYLTRIMETHYLSILANE is a transparent liquid with a density of about 0.763 g/cm³, a boiling point of 89°C (760 mmHg), a refractive index of 1.413, and a vapor pressure of 67.2 mmHg (25°C).

Use:
Propargyltrimethylsilane is mainly used as an alkylating agent in organic synthesis to introduce propynyl or allenyl fragments (containing three carbon atoms) into substrate molecules. Its reactivity is concentrated at both ends of the molecule, and it can generate nitrogen-containing alkyne compounds by forming new C-C bonds, or react with secondary alcohols to generate allene derivatives under specific conditions.
Preparation:
Propynyltrimethylsilane can be synthesised by reacting 1,1,1-trimethyl-2,2-propanedisilane and acetylene under alkaline conditions. The reaction is carried out at low temperatures and typically uses a metal-synthesised base as the catalyst.
Propargyltrimethylsilanes are important in the field of organic synthesis due to their unique reactivity and wide application potential. However, due to its flammability and irritant properties, its use requires strict adherence to safe operating procedures and proper ventilation.

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