CAS:1195768-06-9 | Dabrafenib Mesylate

Products Description

Dabrafenib Mesylate is a white solid that is hygroscopic. It is slightly soluble in DMSO and methanol and needs to be stored at low temperatures and under an inert atmosphere to maintain its stability. Dabrafenib Mesylate (API) should be stored in a refrigerator at -20°C and under an inert atmosphere.

Basic Info

Uses

Dabrafenib Mesylate is a targeted therapy drug, a mitogen-activated protein kinase (MAPK) pathway inhibitor, mainly used in the field of tumor treatment.

• Targeted anticancer therapy: As a BRAF V600E/K mutation inhibitor, it is used to treat solid tumors such as melanoma and non-small cell lung cancer, significantly prolonging patient survival.
• Combination therapy: Often used in combination with trametinib to inhibit the MAPK pathway, reduce drug resistance and improve efficacy (FDA-approved regimen).
• Clinical research expansion: Explore indications for BRAF mutant cancers such as thyroid cancer and colorectal cancer (some are in Phase III trials).
• Drug development standard: As an active pharmaceutical ingredient (API), it is used for generic drug consistency evaluation and new dosage form development (such as nanoformulations).

Packaging & Delivery

• Packaging: 25kg fiber drum with PE inner liner or customized packaging available.
• Delivery Time: 7-10 days after payment confirmation.
• Shipping Methods: By sea, air, or courier (FedEx, DHL, UPS, TNT).

Company Profile

Gneebio With decades of experience in researching, manufacturing and marketing organic chemicals, gneebio is now a global supplier of research, development and manufacturing chemicals. We supply Organic Chemicals, Biochemicals, Pharmaceutical Intermediates, and more. We adhere to the principle of "Quality First" and have obtained ISO 9001 certification. We have also set up a dedicated testing center to implement strict quality control standards at all stages of the production process. Quality inspectors closely monitor the production process of each product to ensure the quality of the final chemical products. We also prioritize safety and environmental protection by using eco-friendlyproduction processes and implementing strict waste management systems.

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