CAS 474645-27-7 | MonoMethyl Auristatin E

Products Description

Monomethyl auristatin E is a synthetic analog of dolastatin 10, which is extremely cytotoxic. It kills tumor cells by destroying the cytoskeletal structure of tumor cells and interfering with mitosis.
Monomethyl auristatin E (MMAE) is a tubulin inhibitor that destroys the microtubule network in cells by inhibiting the polymerization of microtubules, thereby preventing cell division and proliferation.

Basic Info

Uses

Monomethyl Auristatin E is mainly used in the preparation of antibody-drug conjugates (ADCs). ADCs combine MMAE with monoclonal antibodies and use the specific recognition ability of antibodies to guide MMAE to cancer cells for precise treatment. This method can reduce damage to healthy tissues and improve treatment effects.

Company Profile

Gneechem, located in Henan Province, China, is part of the GNEE Group, with 22 years of experience in foreign trade, specializing in providing high-quality chemical raw materials and professional trading services to customers around the world. We supply basic chemical raw materials, fine chemicals and specialty chemicals for a wide range of industries.We are ISO9001 certified and have been recognized by a number of authoritative qualifications at home and abroad, making us a trusted partner of our customers.

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