CAS:5975-18-8 | Tributylammonium Pyrophosphate

The compound corresponding to CAS 5975-18-8 is Tributylammonium Pyrophosphate, with a molecular formula of C24H58N2O7P2, a molecular weight of 548.67 g/mol, and an appearance of white to off-white solid.
Tributylammonium Pyrophosphate has a melting point of 78–83°C, is sensitive to air and moisture, and is easily hygroscopic. It is slightly soluble in polar organic solvents (such as water, methanol, DMSO), insoluble in non-polar solvents, and needs to be stored in a frozen environment and sealed with inert gas to prevent decomposition.

Properties：

1. It is usually a colorless or light yellow transparent liquid, easily soluble in organic solvents such as ether, chloroform and benzene.
2. It is a phosphorus oxide, has electrophilicity and weak acidity, and can form stable complexes with many metals and ligands.

Uses：

As a phosphorylation reagent, Tributylammonium Pyrophosphate is widely used in the synthesis of nucleoside triphosphates, providing structural units for DNA, RNA and sugar nucleotides. In pharmaceutical research and development, it can participate in the enzymatic synthesis of 3'-deoxy-apio-nucleic acid duplexes and is used to prepare fluorescent non-nucleotide ATP analogs. Its hydrophobic tributylammonium cation can increase the solubility of reaction intermediates in organic solvents.

It is recommended to operate in a dry environment to avoid inhalation of dust or contact with skin and mucous membranes. Although existing data show low toxicity, laboratory protection standards must still be followed.

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