CAS:1536473-72-9 | TBuBrettPhos Pd G3

The compound corresponding to CAS 1536473-72-9 is TBuBrettPhos Pd G3, which belongs to the phosphine ligand complex in the palladium catalytic system. Its molecular formula is C44H63NO5PPdS, and its molecular weight is about 854.43 g/mol.
TBuBrettPhos Pd G3 contains di-tert-butylphosphine ligands, which combine with the methoxy and isopropyl groups on the biphenyl skeleton to form a structure with large steric hindrance, which helps the selectivity of palladium catalytic reactions and shows high catalytic performance in organic synthesis.

Properties：

1. It is relatively stable under normal conditions, but may undergo oxidation or decomposition reactions under conditions containing oxygen or high humidity.
2. As an organic compound of palladium, it is often used as a catalyst or intermediate in reactions. It can catalyze many organic reactions, such as hydrogenation, coupling, oxidation, etc.
3. It can usually be dissolved in common organic solvents, such as methanol, ethanol, chloroform, etc.

Uses：

TBuBrettPhos Pd G3 is mainly used for C-C bond coupling reactions such as Suzuki-Miyaura and Negishi coupling, as well as the construction of complex molecules such as nitrogen-containing heterocycles and biphenyl compounds, and is commonly used in the research and development of pharmaceutical intermediates.

1. Toxicity: TBuBrettPhos Pd G3 is a toxic compound. Direct contact or inhalation of large amounts of the substance may cause poisoning symptoms such as difficulty breathing, chest tightness, nausea, vomiting and headache.

2. Irritant: The compound may be irritating to the eyes, skin and respiratory tract.

3. Fire and explosion risk: The compound may burn or explode under conditions of high temperature, open flame or sparks. Avoid contact with combustibles and store in a cool, dry place.

4. Storage and handling: The compound should be stored in a sealed container away from fire and oxidants. Personal protective equipment such as protective gloves, protective glasses and protective masks should be worn when using.

Company establishment time: 2021; Factory area: 3600 square meters. Company area: 800 square meters. Company staff: 200+

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