CAS:1820817-64-8 | APhos Pd G3

APhos Pd G3, also known as methanesulfonate {[4-(N,N-(dimethylamino)phenyl]di-tert-butylphosphino}(2'-amino-1,1'-biphenyl-2-yl)palladium(II), is an organopalladium compound. It belongs to the class of transition metal catalysts and is commonly used in cross-coupling reactions in organic synthesis, such as Suzuki coupling reaction and Buchwald-Hartwig amination reaction.

Properties：

1. Appearance: APhos Pd G3 is a brown crystalline powder.
2. Thermal stability: The compound is relatively stable at room temperature, but may decompose under high temperature and humid conditions.
3. Solubility: The compound is easily soluble in organic solvents (such as dimethylformamide, dichloromethane), but has low solubility in water.
4. Coordination: APhos Pd G3 is a complex in which the phosphine group and the amino group form a coordination bond with the palladium ion through the coordinating atom to form a hexavalent palladium complex.

Uses：

1. APhos Pd G3 has important applications in organic chemistry as a catalyst, especially for forming carbon-carbon bonds and carbon-nitrogen bonds.
2. In addition, due to its special structure and coordination properties, it is also widely used in organic synthesis reactions, especially in catalytic hydrogenation and cross-coupling reactions, showing high catalytic activity.

1. APhos Pd G3 should be stored in a cool, dry place away from light and moisture to prevent chemical degradation.
2. Operate in a well-ventilated environment, such as a fume hood, to reduce the risk of inhaling harmful gases.
3. In case of leakage, take appropriate measures to clean up immediately, use appropriate adsorbent materials for treatment, and dispose of waste in accordance with laboratory safety procedures.
4. Understand the chemical stability of this compound and avoid reactions with strong oxidants, strong reducing agents, or strong acids/bases.

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