CAS 339155-13-4 | 2,3-Pyridinedicarboxylic Acid

The compound corresponding to CAS 339155-13-4 is 2,3-Pyridinedicarboxylic Acid, with a molecular formula of C₇H₅NO₄ and a molecular weight of 167.12 g/mol. It is a pyridine derivative with a dicarboxylic acid structure and has application value in organic synthesis and pharmaceutical intermediates.
2,3-Pyridinedicarboxylic Acid is a white to light yellow prismatic crystal at room temperature and decomposes when heated to 188°C. Its density is 1.551 g/cm³, and its boiling point is about 425°C (760 mmHg). It is easily soluble in water and alkaline solutions, slightly soluble in ethanol, and insoluble in ether and benzene.

Uses

Pharmaceutical intermediates:
Anti-tumor drugs: 2,3-Pyridinedicarboxylic Acid is a precursor for the synthesis of topoisomerase inhibitors (such as camptothecin analogs) and exerts anti-cancer activity by inhibiting DNA replication.
Neuroprotectants: Its derivatives can modulate glutamate receptors (such as NMDA receptors) and are used to treat Alzheimer's disease or stroke.
Antibiotics: Participate in the side chain modification of β-lactam antibiotics (such as cephalosporins) to enhance drug stability.
Materials Science:
Metal-organic frameworks (MOFs): As ligands with metal ions (such as Zr⁴⁺, Zn²⁺) to construct porous materials for gas adsorption or catalysis.
Fluorescent probes: Form complexes with rare earth ions (such as Eu³⁺, Tb³⁺) for bioimaging or sensor design.

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