Acetonitrile (AN) CAS NO. 75-05-8: Specifications And Industrial Uses

Apr 07, 2026 Leave a message

Acetonitrile, also known as methyl cyanide, is a colorless liquid that is very volatile and has a special odor similar to ether. It has excellent solvent properties and can dissolve many kinds of organic, inorganic and gaseous substances. A certain toxicity, with water and alcohol immiscible. Acetonitrile can occur in a typical nitrile reaction and is used to prepare many typical nitrogen compounds.


What is acetonitrile used for in industry?

 

Pharmaceutical Industry

Acetonitrile (AN) is an important organic solvent and chemical intermediate widely used in the pharmaceutical industry. It serves as a reaction medium and extraction solvent in the synthesis and purification of pharmaceuticals, including vitamins, corticosteroids (such as cortisone), vitamin B1, and amino acids. It is also used in melamine-related chemical processes and various intermediates.

 

Analytical Chemistry (HPLC Grade Solvent)

Acetonitrile is one of the most important HPLC (High-Performance Liquid Chromatography) solvents, widely used in laboratories and research institutions.
It provides:

  • High UV transparency
  • Low viscosity for accurate analysis
  • Stable baseline in chromatographic systems

 

Chemical Manufacturing

Used as a reaction medium and extraction solvent in organic synthesis, Acetonitrile helps improve reaction efficiency and product purity.
Applications include:

  • Fine chemical production
  • Agrochemical synthesis
  • Industrial intermediate processing

 

Other Applications

  • Acetonitrile is also used in lithium battery electrolytes and high-tech materials, supporting modern energy storage development.
  • AN is also used as a solvent for vinyl coatings, as an extractant for fatty acids, as an alcohol denaturant, as a butadiene extractant, and as an acrylonitrile synthetic fiber.
  • There are many uses in textile dyeing, lighting, perfumery and photographic materials.

 

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Specification or COA of Acetonitrile (AN)

 

Items Specification Test Result
Appearance Transparent liquid without suspended matter Qualified
Chroma (Pt-Co) / number ≤10 5.0
Water w/% ≤0.03 0.010
Total cyanide (calculated as hydrocyanic acid) / (mg/kg) ≤10 2.0
Acetone / (mg/kg) ≤25 1.0
Acrylonitrile / (mg/kg) ≤25 1.0
Heavy component (including propionitrile) / (mg/kg) ≤500 48.0
Purity w/% ≥99.9 99.97
Ammonia / (mg/kg) ≤6 0.1
Acidity (as acetic acid) / (mg/kg) ≤50 7.7
Density (20°C) g/cm³ 0.781–0.784 0.782
Copper / (mg/kg) ≤0.5 0.01
Iron / (mg/kg) ≤0.5 0.02
Boiling Range (Under 0.10133 MPa) °C 81.0–82.0 81.0–81.2

 

 

Conclusion

 

Tianjin Gnee Biotech Co., Ltd., as a dedicated manufacturer and supplier, is committed to providing high-purity Acetonitrile (AN) that meets strict quality standards.

We welcome your inquiries about our wholesale Ethyl Acetate pricing and look forward to supporting your manufacturing needs. Contact our sales team today to discuss your Acetonitrile (AN) CAS NO. 75-05-8 requirements and receive a competitive quote.

 

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